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Todavía hay sobrevivientes entre las ruinas — debemos cuidarlos y curarlos. Para mantenernos adelante de la plaga, debemos implementar nuevos inventos y tecnologías. Nuestra influencia se expandirá conforme reconstruimos, pero la plaga seguirá acechando en las sombras, lista para atacar cuando menos la esperemos. Cuando lo haga, será difícil adaptarse, pero sobreviviremos. Además de la adquisición de recursos importantes, nuestro imperativo será controlar la plaga.\u003C\u002Fp>\n\n\u003Cp>En \u003Cem>\u003Cstrong>Pest\u003C\u002Fstrong>\u003C\u002Fem>, los jugadores toman los papeles de líderes de las casas gobernantes de un otrora gran imperio que fue golpeado por una plaga catastrófica. La plaga ha dejado gran parte del imperio en ruinas, así que ahora le corresponde a los jugadores restaurarlo a su gloria anterior.\u003C\u002Fp>\n\n\u003Cp>\u003Cem>Pest\u003C\u002Fem> se juega en 6 rondas. Cada ronda antes de que los jugadores tomen su turno, se revelará una carta de plaga que muestra cómo se propagará la plaga en esa ronda. En su turno, los jugadores podrán seleccionar entre muchas acciones en su tablero de jugador usando un sistema único de selección de acciones. Así, los jugadores podrán mover su equipo de contención en el tablero, poner en cuarentena y curar personas infectadas, reconstruir, asignar trabajadores, cosechar recursos y más. Conforme la influencia de su casa crece, los jugadores podrán jugar más acciones, generar más recursos y albergar más personas. 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